Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Find your homesteading haven in Powell County, located in Eastern Kentucky with Stanton serving as the county seat. With a modest population of 12,200, this area is ideal for buyers desiring serene landscapes, proximity to natural attractions like Natural Bridge State Park, and a peaceful, rural setting.