Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Situated in Eastern Kentucky, Lewis County, with Vanceburg as its seat and a population of about 13,275, features a landscape dotted with rolling hills and access to the Ohio River, providing land buyers with tranquil settings and opportunities for farming or recreational use.