Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Experience the charm of North Central Kentucky in Henry County, with its county seat in New Castle. This community of roughly 16,126 people provides a welcoming atmosphere for land buyers interested in rural living, farming, or creating a private retreat with a strong sense of local heritage.