Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Explore the fertile plains of Western Kentucky in Henderson County, anchored by the vibrant city of Henderson. Home to approximately 45,210 residents, this county boasts rich agricultural land and riverfront opportunities, making it a prime location for those looking to establish a farm or develop property with access to transportation routes.